Brain Microbiome: The Intestinal Bacterium Of The Human Brain

Bacteria have been found in the study of the human brain, but there is no explanation for how they got there. It is also not known whether they are beneficial or harmful. It is even suspected that they can affect mood and personality.
Brain microbiome: an intestinal bacterium in the human brain

During the last annual meeting of the University of Alabama Neuroscience community in Birmingham, researchers presented a report that showed that different areas of the human brain, i.e., some intestinal bacteria. They were thought to be brain microbiomes.

The finding is both fascinating and scary. However, there is no explanation yet for how the bacteria entered the brain or whether they were beneficial or harmful. Experts even believed that they could affect mood and perhaps also personality.

What is an intestinal microbiome?

The intestinal microbiome is a microbial culture that lives in the intestine. There are about one hundred thousand trillion species of bacteria. They, in turn, are made up of more than three million genes. People share only a third of them all. The rest are specific to each individual. The intestinal microbiome is an important part of every person’s identity.

Some of its main functions are the regulation of the immune system, the absorption of nutrients, and the management of external pathogens. Any change in the intestinal microbiome can cause autoimmune diseases, allergies, or inflammation. In fact, researchers have also linked it to Alzheimer’s and Parkinson’s disease.

On the other hand, the imbalance of this intestinal culture creates endotoxins, high acid levels, and accumulated belly fat. In addition, chronic inflammation causes cardiovascular problems and diabetes.

While microbes and bacteria are feared globally, the truth is that we cannot live without them. While you may not be aware of it, there are trillions of living beings inside your body.

intestinal bacteria

Brain microbiome

Scientists have begun to wonder how these bacteria get into the brain, as the cerebral blood barrier protects them.

The cerebral blood barrier is a protection system against the entry of foreign substances. It allows water, lipid-soluble molecules, and some gases to pass through it. It also lets through selected amino acids and other molecules. But the bacteria contained in the human brain are for the most part in the gut.

They are glial cells that support neurons and astrocytes and prevent neurotoxins and other substances from entering the brain. When these harmful substances manage to penetrate the barrier in some way, they usually cause inflammation with very negative and even fatal consequences. But the fun is, astrocytes seem to be a favorite place for these intestinal bacteria to live in the brain.

Researchers have found that the bacteria can pass through the intestinal nerves, cerebral blood barrier or nose. However, the real reason is still unknown. This potential brain microbiome in the human brain still needs to be studied extensively.

bacteria

Human brain research

Dr. Rosalinda Roberts and her team from the Department of Psychiatry and Behavioral Neurobiology at the University of Alabama are responsible for this finding. They study the brains of 34 people. Half of the brain was healthy and the other half suffered from schizophrenia. In addition, they conducted a parallel study with mice to rule out the possibility that the bacteria would only occur after death or that the studies had defects caused by contamination.

In both studies, the researchers found the presence of bacteria in the brains of humans and mice in non-infectious or traumatic situations. In fact, they found them in several areas of the brain. Mainly in the blackhead nucleus, hippocampus, and forebrain block. None of the brains they examined also showed inflammation.

These results have left the door open for speculation and new brain microbiome studies. The possibility that brain microbiome is associated with behavior, mood, and some neurological diseases is currently being considered.

Photos provided by Rosalinda Roberts, Courtney Walker and Charlene Farmer.

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